Lab-created Blood Products for von Willebrand Disease

Recombinant products are made of proteins created in a laboratory using a process known as recombinant technology. These products are not made from human blood. Recombinant products may offer a safer option than plasma-derived products because they avoid potential blood-borne transmission of infectious diseases.

In the US, there is only one recombinant form of von Willebrand factor commercially available. Unlike plasma-derived products, recombinant von Willebrand factor does not contain factor VIII.  This type of von Willebrand factor is packaged similar to the plasma-derived product and comes as a powder that is combined with liquid when ready to use.